Well-established research lines at DiSLL cover the following specific domains:

• Italian Studies and Italian Philology
• Comparative Literature and Theory of Literature
• Italian Linguistics, History of the Italian language, Italian Metrics and Stylistics
• Romance Philology
• Mediaeval and Renaissance Latin Literature
• Ancient Greek Language and Literature
• Byzantine Philology
• Germanic Philology
• Slavic Philology
• Historical and General Linguistics
• English and Anglo-American Languages, Literature and Cultures
• Germanic Languages, Literature and Cultures
• French Languages, Literature and Cultures
• Castilian and Latin American Spanish Languages, Literature and Cultures
• European and Brazilian Portuguese Language and Literature
• Galician Language and Literature
• Romanian Language and Literature
• Slavic studies –Russian, Serbian and Croatian, Slovenian, Czech and Slovak, Polish Language and Literature
• Hungarian Language and Literature
• Drama and Theatre, Music, Television and Audiovisual Media Studies

DiSLL also promotes research into fields such as Intercultural Studies, Gender and Post-Colonial Studies, Translation Studies, Literary and Specialized Translation, Media Studies, Corpus Linguistics and E-learning.
Research lines are directly connected with the activity that is carried out by numerous research groups and within the framework of either European (e.g. ERC – Starting Grant) or national (e.g. PRIN, FIRB, regional funding opportunities, etc.) projects.